MICCAI 2019

MICCAI 2019 DAILY Carole Sudre or reduce. That makes the full supply and they don’t have the same ability to adapt, to expand to the brain more difficult. In the end, it causes these different markers in the brain. Is your work to know what is happening in the brain or to prevent what happens? Well, both. If we want to prevent, we need to understand why it happens. To understand why it happens, we need to also detect where they are. All those things are very tightly related. The first thing is trying to detect them and then characterize them. Then actually using this characterization, you can better distinguish them from one another and understand what drives the thing to happen. Further down the line, you have what new things will do to the blood vessels, how will they evolve, and what will be the consequence in terms of cognition. especially in the lesions that I’m looking into. Since they can be anywhere in the brain, you have also this relationship between where they will appear and what they will produce in terms of the clinical symptoms and cognitive symptoms in particular. Can we treat that with medicine to improve the symptoms? That’s the ultimate goal. That we can only do when we understand where it comes from. What is a lacunar space? A lacunar space is the kind of thing you observe in the brain, especially in the white matter, that is due to a small ischemia. In that area, the brain lacked oxygen completely at some point so the tissue is destroyed. What we see when we say lacunar space is this absence of tissue, the scar that results from ischemia. What does it prevent people from doing? It depends. These things happen in a lot of situations. They are actually very difficult to detect. They are not like other subtypes of vascular lesions or changes that we see in the brain. For radiologists, it is something that is extremely difficult to assess and to say that it’s really a lacunar, in fact, instead of other subtypes of changes that happen in the brain that are not problematic. What is very important is that you have some of them that 15