Olivia Sandvold is a fourth-year bioengineering PhD student at the University of Pennsylvania. Her paper, demonstrating a novel hybrid spectral CT system to reduce error in iodine quantification, has just won the Physics of Medical Imaging Best Paper Award at SPIE Medical Imaging. This impressive young woman is here to tell us all about it. Computer Vision News 36 Physics of Medical Imaging Best Paper Hybrid spectral CT system with clinical rapid kVp-switching X-ray tube and dual-layer detector for improved iodine quantification In this paper, Olivia introduces a new multi-energy hybrid CT system. It combines a traditional kVp switching X-ray tube source, which alternates between various energy levels emitted from the Xray tube, with a dual-layer or sandwich detector, a spectral detector that discriminates energy into upper and lower domains. The work demonstrates that joining these technologies and leveraging the properties of the multiple channels acquired can reduce errors in iodine quantification, which is important in clinical diagnoses. Physicians use iodine contrast to measure increased uptake from the bloodstream or the oral pathway into different body cavities. If accurate, these measurements can act as quantitative biomarkers for disease.
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