Computer Vision News - September 2019

Project by RSIP Vision 10 Every month, Computer Vision News reviews a successful project. Our main purpose is to show how diverse image processing techniques contribute to solving technical challenges and real world constraints. This month we review challenges and solutions in a Pharma project by RSIP Vision: Multiplex. by Dorin Yael Immunoh i s t ochemi s t r y is a powerful tool allowing the investigation of protein expression, activation and distribution within a tissue slice. Multiplex immunohistochemistry allows to repeat this process for multiple markers in the same individual slice, maximizing the amount of information acquired in it. This unique process maintains the spatial structure of the tissue and allows the identification of different cell types and subtypes, allowing in turn the investigation of from sub-cell to tissue, and their interaction and co-localization. The main tasks performed in the analysis of this rich information are detection, segmentation and classification, which can be performed either on single cells, in order to know the type of cell, its size, location, quantity and more; or on the whole tissue. After that, it is possible to integrate the data obtained through the staining and understand the relation between the single cells and the tissue.